GATE BT Masterclass: Fundamentals of Biological Engineering

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About Course

This course is part of the GATE Biotechnology Complete Preparation Bundle and is designed to provide a strong foundation in Fundamentals of Biological Engineering for GATE Biotechnology aspirants. The course comprehensively covers Engineering Principles Applied to Biological Systems, Classical Thermodynamics and Bioenergetics, and Transport Processes as prescribed in the latest GATE BT syllabus. It includes detailed lecture notes for conceptual clarity and problem-solving skills enhancement, along with systematically solved Previous Year Questions (PYQs) with detailed explanations. Students will also gain access to practice problems, numerical discussions, and mock tests to strengthen exam preparation, improve analytical thinking, and build confidence for achieving high scores in GATE Biotechnology.

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What Will You Learn?

  • Understand material and energy balance calculations in biological systems
  • Learn recycle, bypass, and purge process analysis
  • Master stoichiometry of microbial growth and product formation
  • Understand thermodynamics and bioenergetics concepts for GATE BT
  • Learn phase equilibria, reaction equilibria, and membrane potential
  • Develop understanding of fluid flow and transport phenomena
  • Study mixing, oxygen transfer, and kLa in bioreactors
  • Understand heat transfer, LMTD, and heat exchangers
  • Practice GATE PYQs with detailed solution explanations
  • Improve numerical problem-solving and exam preparation skills

Course Content

Engineering Principles Applied to Biological Systems
Material and energy balances for reactive and non-reactive systems; Recycle, bypass and purge processes; Stoichiometry of growth and product formation; Degree of reduction, electron balance and theoretical oxygen demand.

Classical Thermodynamics and Bioenergetics
Laws of thermodynamics; Solution thermodynamics; Phase equilibria, reaction equilibria; Ligand binding; Membrane potential; Energetics of metabolic pathways, oxidation and reduction reactions.

Transport Processes
Newtonian and non-Newtonian fluids, fluid flow - laminar and turbulent; Mixing in bioreactors, mixing time; Molecular diffusion and film theory; Oxygen transfer and uptake in bioreactor, $k_{La}$ and its measurement; Conductive and convective heat transfer, LMTD, overall heat transfer coefficient; Heat exchangers.

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